Article
Apolipoprotein E4 Allele and Gait Performance in Mild Cognitive Impairment: Results From the Gait and Brain Study.
The journals of gerontology. Series A, Biological sciences and medical sciences - 9 Nov 2017
Sakurai Ryota, Montero-Odasso Manuel
Abstract excerpt
BACKGROUND: The apolipoprotein E polymorphism ε4 allele (ApoE4) and gait impairment are both known risk factors for developing cognitive decline and dementia. However, it is unclear the interrelationship between these factors, particularly among older adults with mild cognitive impairment (MCI) who are considered as prodromal for Alzheimer's disease. This study aimed to determine whether ApoE4 carrier individuals...
Topics
- Aged
- Alleles
- Apolipoprotein E4
- Cognitive Dysfunction
- Female
- Gait
- Humans
- Longitudinal Studies
- Male
- Prospective Studies