Article
Mysm1 expression in the bone marrow niche is not essential for hematopoietic maintenance.
Experimental hematology - 1 Mar 2017
Petrov Jessica C, Nijnik Anastasia
Abstract excerpt
Myb-Like SWIRM and MPN domains 1 (MYSM1) is a chromatin-binding protein, essential for hematopoietic stem cell (HSC) maintenance and differentiation in humans and mouse models. HSCs in mammalian bone marrow exist in close interactions with many non-hematopoietic cell types in their microenvironment, collectively known as the bone marrow niche. Although cell-intrinsic activities of MYSM1 within the hematopoietic...
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