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Article

Endothelial and perivascular cells maintain haematopoietic stem cells.

Nature - 25 Jan 2012

Ding Lei, Saunders Thomas L, Enikolopov Grigori, Morrison Sean J

Abstract excerpt

Several cell types have been proposed to create niches for haematopoietic stem cells (HSCs). However, the expression patterns of HSC maintenance factors have not been systematically studied and no such factor has been conditionally deleted from any candidate niche cell. Thus, the cellular sources of these factors are undetermined. Stem cell factor (SCF; also known as KITL) is a key niche component that maintains...

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Identifiers

PMID: 22281595
DOI: 10.1038/nature10783
PMCID: PMC3270376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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