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Article

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

BMC musculoskeletal disorders - 9 Nov 2016

Stubelius Alexandra, Andersson Annica, Holmdahl Rikard, Ohlsson Claes, Islander Ulrika, Carlsten Hans

Abstract excerpt

BACKGROUND: Increased reactive oxygen species and estrogen deficiency contribute to the pathophysiology of postmenopausal osteoporosis. Reactive oxygen species contribute to bone degradation and is necessary for RANKL-induced osteoclast differentiation. In postmenopausal bone loss, reactive oxygen species can also activate immune cells to further enhance bone resorption. Here, we investigated the role of reactive...

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Identifiers

PMID: 27829407
DOI: 10.1186/s12891-016-1315-1
PMCID: PMC5103594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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