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Article

The Effect of Preservative and Temperature on the Analysis of Circulating Tumor DNA.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2017

Parpart-Li Sonya, Bartlett Bjarne, Popoli Maria, Adleff Vilmos, Tucker Laura, Steinberg Rebecca, Georgiadis Andrew, Phallen Jill, Brahmer Julie, Azad Nilo, Browner Ilene, Laheru Daniel, Velculescu Victor E, Sausen Mark, Diaz Luis A

Abstract excerpt

Purpose: Analysis of genomic alterations in cell-free DNA (cfDNA) is evolving as an approach to detect, monitor, and genotype malignancies. Methods to separate the liquid from the cellular fraction of whole blood for circulating tumor DNA (ctDNA) analyses have been largely unstudied, although these may be a critical consideration for assay performance.Experimental Design: To evaluate the influence of blood...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27827317
DOI: 10.1158/1078-0432.CCR-16-1691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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