Article
Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA.
Clinical biochemistry - 1 Oct 2015
Toro Patricia Valda, Erlanger Bracha, Beaver Julia A, Cochran Rory L, VanDenBerg Dustin A, Yakim Elizabeth, Cravero Karen, Chu David, Zabransky Daniel J, Wong Hong Yuen, Croessmann Sarah, Parsons Heather, Hurley Paula J, Lauring Josh, Park Ben Ho
Abstract excerpt
OBJECTIVES: Circulating plasma DNA is being increasingly used for biomedical and clinical research as a substrate for genetic testing. However, cell lysis can occur hours after venipuncture when using standard tubes for blood collection, leading to an increase in contaminating cellular DNA that may hinder analysis of circulating plasma DNA. Cell stabilization agents can prevent cellular lysis for several days,...
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