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Article

Assessment of Pre-Analytical Sample Handling Conditions for Comprehensive Liquid Biopsy Analysis.

The Journal of molecular diagnostics : JMD - 1 Aug 2020

Gerber Teresa, Taschner-Mandl Sabine, Saloberger-Sindhöringer Lisa, Popitsch Niko, Heitzer Ellen, Witt Volker, Geyeregger René, Hutter Caroline, Schwentner Raphaela, Ambros Inge M, Ambros Peter F

Abstract excerpt

Liquid biopsies as a minimally invasive approach have the potential to revolutionize molecular diagnostics. Yet, although protocols for sample handling and the isolation of circulating tumor DNA (ctDNA) are numerous, comprehensive guidelines for diagnostics and research considering all aspects of real-life multicenter clinical studies are currently not available. These include limitations in sample volume,...

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Identifiers

PMID: 32497717
DOI: 10.1016/j.jmoldx.2020.05.006

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