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Evaluation of pre-analytical factors affecting plasma DNA analysis

2017-04-18

Abstract excerpt

Pre-analytical factors can significantly affect circulating cell-free DNA (cfDNA) analysis. However, there are few robust methods to rapidly assess sample quality and the impact of pre-analytical processing. To address this gap and to evaluate effects of DNA extraction methods and blood collection tubes on cfDNA yield and fragment size, we developed a multiplexed droplet digital PCR (ddPCR) assay with 5 short and...

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Literature Corpus work
fae1c684-634d-5220-a7c4-3628c64fe1e9
DOI
10.1101/126839
Open publication

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Evaluation of pre-analytical factors affecting plasma DNA analysisDOI 10.1101/126839
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