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Circulating tumoral DNA: Preanalytical validation and quality control in a diagnostic laboratory

11 Nov 2017

Abstract excerpt

We present the results of our technical validation process in establishing the analysis of circulating tumor DNA (ctDNA) as a diagnostic tool. Like most cells in our body, tumor cells shed DNA in the blood flow. Analysis of ctDNA mutational content can provide invaluable information on the genetic makeup of a tumor, and assist oncologists in deciding on therapy, or in following residual disease. However, low...

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PMID: 29137972
DOI: 10.1016/j.ab.2017.11.004

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