Article
Developing Quality Programs for Cell-Free DNA (cfDNA) Extraction from Peripheral Blood.
The journal of applied laboratory medicine - 1 Jul 2020
Samoila Aliaksandra, Sosa Jose, Padilla Jessica, Wutkowski Michael, Vanness Katelynd, Viale Agnes, Berger Michael, Houck-Loomis Brian, Pessin Melissa, Peerschke Ellinor I
Abstract excerpt
BACKGROUND: Cell-free DNA (cfDNA) analysis using peripheral blood represents an exciting, minimally invasive technology for cancer diagnosis and monitoring. The reliability of testing is dependent on the accuracy and sensitivity of specific molecular analyses to detect tumor-associated genomic variants and on the quantity and quality of cfDNA available for testing. Specific guidelines for standardization and...
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