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Article

Limited genetic diversity in the PvK12 Kelch protein in Plasmodium vivax isolates from Southeast Asia.

Malaria journal - 8 Nov 2016

Wang Meilian, Siddiqui Faiza Amber, Fan Qi, Luo Enjie, Cao Yaming, Cui Liwang

Abstract excerpt

BACKGROUND: Artemisinin resistance in Plasmodium falciparum has emerged as a major threat for malaria control and elimination worldwide. Mutations in the Kelch propeller domain of PfK13 are the only known molecular markers for artemisinin resistance in this parasite. Over 100 non-synonymous mutations have been identified in PfK13 from various malaria endemic regions. This study aimed to investigate the genetic...

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Identifiers

PMID: 27821166
DOI: 10.1186/s12936-016-1583-0
PMCID: PMC5100195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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