Article
Genetic diversity of the Pvk12 gene in Plasmodium vivax from the China-Myanmar border area.
Malaria journal - 4 Nov 2016
Deng Shuang, Ruan Yonghua, Bai Yao, Hu Yue, Deng Zeshuai, He Yongshu, Ruan Rui, Wu Yanrui, Yang Zhaoqing, Cui Liwang
Abstract excerpt
BACKGROUND: Plasmodium falciparum resistance to artemisinin emerged in the Greater Mekong Sub-region has been associated with mutations in the propeller domain of the kelch gene Pfk13. METHODS: Here the polymorphisms in Pvk12 gene, the orthologue of Pfk13 in Plasmodium vivax, were determined by PCR and sequencing in 262 clinical isolates collected in recent years (2012-2015) from the China-Myanmar border area....
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