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Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing.

Antimicrobial agents and chemotherapy - 1 Mar 2017

Talundzic Eldin, Ndiaye Yaye D, Deme Awa B, Olsen Christian, Patel Dhruviben S, Biliya Shweta, Daniels Rachel, Vannberg Fredrik O, Volkman Sarah K, Udhayakumar Venkatachalam, Ndiaye Daouda

Abstract excerpt

The emergence of Plasmodium falciparum resistance to artemisinin in Southeast Asia threatens malaria control and elimination activities worldwide. Multiple polymorphisms in the P. falciparum kelch gene found in chromosome 13 (Pfk13) have been associated with artemisinin resistance. Surveillance of potential drug resistance loci within a population that may emerge under increasing drug pressure is an important...

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Antimalarials
Artemisinins
Drug Resistance
Epidemiological Monitoring
Malaria, Falciparum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmodium falciparum

Protozoan Proteins

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PMID: 28069653
DOI: 10.1128/AAC.02116-16
PMCID: PMC5328579

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Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing.PMID 28069653Read ↗

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