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Article

Experimental Evolution of Metabolic Dependency in Bacteria.

PLoS genetics - 1 Nov 2016

D'Souza Glen, Kost Christian

Abstract excerpt

Bacteria frequently lose biosynthetic genes, thus making them dependent on an environmental uptake of the corresponding metabolite. Despite the ubiquity of this 'genome streamlining', it is generally unclear whether the concomitant loss of biosynthetic functions is favored by natural selection or rather caused by random genetic drift. Here we demonstrate experimentally that a loss of metabolic functions is...

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Share to Directed Molecular Evolution
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27814362
DOI: 10.1371/journal.pgen.1006364
PMCID: PMC5096674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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