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Article

Cellular Model of p21-Induced Senescence.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Shtutman Michael, Chang Bey-Dih, Schools Gary P, Broude Eugenia V

Abstract excerpt

Cellular senescence is a unique process of normal physiology, from embryonic development to aging, also known for its association with a broad range of pathological conditions. Therefore a reliable model of cellular senescence remains an indispensable tool for the investigation of senescence-associated changes and human disease. Here we describe a model of HT1080 fibrosarcoma cells with an inducible senescence...

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Identifiers

PMID: 27812865
DOI: 10.1007/978-1-4939-6670-7_3
PMCID: PMC6764449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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