Article
Senescence Phenotypes Induced by Ras in Primary Cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Lau Lena, David Gregory
Abstract excerpt
Cellular senescence is defined as a state of stable cell-cycle arrest that is distinct from quiescence and terminal differentiation. Many stimuli can induce senescence, including telomere shortening and oncogene activation. The phenotypes elicited by pro-senescent signals can be heterogeneous depending on the stimulus and the cell type affected. To date, there is not a definitive marker that can ubiquitously and...
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