Article
Minimal change nephrotic syndrome and prohibitin-2 gene polymorphism.
Clinical and experimental nephrology - 1 Aug 2017
Sugimoto Keisuke, Miyazawa Tomoki, Miyazaki Kohei, Yanagida Hidehiko, Enya Takuji, Nishi Hitomi, Wada Norihisa, Okada Mitsuru, Takemura Tsukasa
Abstract excerpt
BACKGROUND: Patients with minimal change nephrotic syndrome (MCNS) often also have allergic diseases. Abnormalities of Th2-derived cytokines and T-cell functions contribute to development of these diseases. On the other hand, imbalances between reactive oxygen species (ROS) and antioxidants have been implicated in MCNS and progression of atopic dermatitis. ROS, produced mainly within mitochondria, subject cells...
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