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Article

Polymorphisms of interleukin-4--related genes in Japanese children with minimal change nephrotic syndrome.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Aug 2003

Kobayashi Yasuko, Arakawa Hirokazu, Suzuki Michiko, Takizawa Takumi, Tokuyama Kenichi, Morikawa Akihiro

Abstract excerpt

BACKGROUND: Minimal change nephrotic syndrome (MCNS) in children frequently is associated with allergy and immunoglobulin E production. T Helper subtype 2 cytokines, such as interleukin-4 (IL-4), may have an important role in the development of atopy. We investigated the associations of gene polymorphisms of IL-4, its receptor (IL-4R), and the signal transducer and activator 6 (STAT6) gene with MCNS. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12900808
DOI: 10.1016/s0272-6386(03)00652-8

Genes

STAT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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