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Article

Genetic effect of the NPHS2 gene variants on proteinuria in minimal change disease and immunoglobulin A nephropathy.

Nephrology (Carlton, Vic.) - 1 Dec 2009

Zhu Li, Yu Lei, Wang Chen-Dan, Lv Ji-Cheng, Li Gui-Sen, Zhang Hong, Wang Hai-Yan

Abstract excerpt

BACKGROUND: Proteinuria varies in different glomerular diseases and even the same one. Podocin, encoded by gene NPHS2, is important in maintaining the integrity of slit diaphragm structure and avoiding proteinuria. Presently, case-control association studies were performed to investigate the genetic effect of variants in NPHS2 in a mass proteinuric glomerulopathy, minimal change disease (MCD) at first, followed...

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Source

Identifiers

PMID: 20025681
DOI: 10.1111/j.1440-1797.2009.01109.x

Genes

NPHS2

Variants

rs3738423

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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