Article
GSTT1 gene abnormality in minimal change nephrotic syndrome with elevated serum immunoglobulin E.
Clinical nephrology - 1 Apr 2012
Miyazaki Kohei, Sugimoto Keisuke, Tsuji Shoji, Iharada Anna, Fujita Shinsuke, Yanagida Hidehiko, Sakata Naoki, Okada Mitsuru, Kaneko Kazunari, Takemura Tsukasa
Abstract excerpt
INTRODUCTION: Imbalance between T-helper 1 (Th1) and 2 (Th2) lymphocytes and effects of reactive oxygen species (ROS) upon glomerular capillary walls have been implicated in minimal change nephrotic syndrome (MCNS). METHODS: By polymerase chain reaction and comparative genomic hybridization, we evaluated mutations of the GSTT1 gene (GSTT1), a member of the glutathione S-transferase (GST) supergene family...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
