Article
Genetic susceptibility to rheumatoid arthritis and its implications for novel drug discovery.
Expert opinion on drug discovery - 1 Aug 2016
Yarwood Annie, Eyre Steve, Worthington Jane
Abstract excerpt
INTRODUCTION: Over 100 susceptibility loci have now been identified for rheumatoid arthritis (RA), several of which are already the targets of approved RA therapies providing proof of concept for the use of genetics in novel drug development for RA. Determining how these loci contribute to disease will be key to elucidating the mechanisms driving disease development, which has the potential for major impact on...
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