Article
The evolution in our understanding of the genetics of rheumatoid arthritis and the impact on novel drug discovery.
Expert opinion on drug discovery - 1 Jan 2020
Machaj Filip, Rosik Jakub, Szostak Bartosz, Pawlik Andrzej
Abstract excerpt
Introduction: Rheumatoid arthritis (RA) is an autoimmune disease that is characterized by chronic inflammation of the joints and affects 1% of the population. Polymorphisms of genes that encode proteins that primarily participate in inflammation may influence RA occurrence or become useful biomarkers for certain types of anti-rheumatic treatment.Areas covered: The authors summarize the recent progress in our...
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