Article
[Genetic factors of rheumatoid arthritis].
Clinical calcium - 1 Dec 2015
Yamamoto Kazuhiko
Abstract excerpt
Rheumatoid arthritis(RA)is one of common autoimmune diseases. As with other complex disorders, recent genome-wide association studies(GWASs)have greatly contributed to our understanding of RA etiology. In this review, the genetic configuration of RA as revealed through GWASs is described. In addition, I discuss the pathologic mechanisms of RA as suggested by the findings of genetic and functional studies of...
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