Rheumatoid arthritis genetics: 2009 update.

doi:10.1007/s11926-009-0050-0

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Article

Rheumatoid arthritis genetics: 2009 update.

Current rheumatology reports - 1 Oct 2009

Plenge Robert M

Abstract excerpt

Recent human genetic discoveries have increased our understanding of rheumatoid arthritis (RA) susceptibility. Genome-wide association studies have expanded the number of validated RA risk loci beyond HLA-DRB1 "shared epitope" alleles to include additional major histocompatibility complex (MHC) risk alleles and more than 10 regions outside the MHC. The newly discovered risk alleles are common in the general...

Topics

Arthritis, Rheumatoid
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Immunogenetics
Major Histocompatibility Complex
Precision Medicine

Source

Open in PubMed

Identifiers

PMID: 19772830
DOI: 10.1007/s11926-009-0050-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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