Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs.

doi:10.1002/mc.22585

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Article

Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs.

Molecular carcinogenesis - 1 Apr 2017

Zhou Fei, Wang Yanru, Liu Hongliang, Ready Neal, Han Younghun, Hung Rayjean J, Brhane Yonathan, McLaughlin John, Brennan Paul, Bickeböller Heike, Rosenberger Albert, Houlston Richard S, Caporaso Neil, Landi Maria Teresa, Brüske Irene, Risch Angela, Ye Yuanqing, Wu Xifeng, Christiani David C, Goodman Gary, Chen Chu, Amos Christopher I, Wei Qingyi

Abstract excerpt

PURPOSE: mRNA degradation is an important regulatory step for controlling gene expression and cell functions. Genetic abnormalities involved in mRNA degradation genes were found to be associated with cancer risks. Therefore, we systematically investigated the roles of genetic variants in the general mRNA degradation pathway in lung cancer risk. EXPERIMENTAL DESIGN: Meta-analyses were conducted using summary data...

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PMID: 27805284
DOI: 10.1002/mc.22585
PMCID: PMC5354966

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CNOT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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