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Article

Structural basis for DNA recognition by STAT6.

Proceedings of the National Academy of Sciences of the United States of America - 15 Nov 2016

Li Jing, Rodriguez Jose Pindado, Niu Fengfeng, Pu Mengchen, Wang Jinan, Hung Li-Wei, Shao Qiang, Zhu Yanping, Ding Wei, Liu Yanqing, Da Yurong, Yao Zhi, Yang Jie, Zhao Yongfang, Wei Gong-Hong, Cheng Genhong, Liu Zhi-Jie, Ouyang Songying

Abstract excerpt

STAT6 participates in classical IL-4/IL-13 signaling and stimulator of interferon genes-mediated antiviral innate immune responses. Aberrations in STAT6-mediated signaling are linked to development of asthma and diseases of the immune system. In addition, STAT6 remains constitutively active in multiple types of cancer. Therefore, targeting STAT6 is an attractive proposition for treating related diseases. Although...

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Source

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Identifiers

PMID: 27803324
DOI: 10.1073/pnas.1611228113
PMCID: PMC5135355

Genes

STAT6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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