Article

If You Cannot Win Them, Join Them: Understanding New Ways to Target STAT3 by Small Molecules

2019-05-28

Abstract excerpt

Signal transducer activator of transcription 3 (STAT3) is among the most investigated oncogenic transcription factors, as it is highly associated with cancer initiation, progression, metastasis, chemoresistance, and immune evasion. The recent evidence from both preclinical and clinical studies have demonstrated that STAT3 plays a critical role in several malignancies associated with poor prognosis such as glioblas...

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Literature Corpus work: 1fdb1163-1ced-5fcb-9b24-743f732582bc
DOI: 10.26434/chemrxiv.8191190.v1

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