Article
Crystal structure of unphosphorylated STAT3 core fragment.
Biochemical and biophysical research communications - 12 Sept 2008
Ren Zhiyong, Mao Xiang, Mertens Claudia, Krishnaraj Ravi, Qin Jie, Mandal Pijus K, Romanowski Michael J, McMurray John S, Chen Xiaomin
Abstract excerpt
Signal transducers and activators of transcription (STATs) are latent cytoplasmic transcriptional factors that play an important role in cytokine and growth factor signaling. Here we report a 3.05 A-resolution crystal structure of an unphosphorylated STAT3 core fragment. The overall monomeric str...
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