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Article

Drosophila IRBP bZIP heterodimer binds P-element DNA and affects hybrid dysgenesis.

Proceedings of the National Academy of Sciences of the United States of America - 15 Nov 2016

Francis Malik Joseph, Roche Siobhan, Cho Michael Jeffrey, Beall Eileen, Min Bosun, Panganiban Ronaldo Paolo, Rio Donald C

Abstract excerpt

In Drosophila, P-element transposition causes mutagenesis and genome instability during hybrid dysgenesis. The P-element 31-bp terminal inverted repeats (TIRs) contain sequences essential for transposase cleavage and have been implicated in DNA repair via protein-DNA interactions with cellular proteins. The identity and function of these cellular proteins were unknown. Biochemical characterization of proteins...

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Identifiers

PMID: 27799520
DOI: 10.1073/pnas.1613508113
PMCID: PMC5135294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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