Article
Mutational analysis of the Drosophila DNA repair and recombination gene mei-9.
Genetics - 1 May 2004
Yildiz Ozlem, Kearney Hutton, Kramer Benjamin C, Sekelsky Jeff J
Abstract excerpt
Drosophila mei-9 is essential for several DNA repair and recombination pathways, including nucleotide excision repair (NER), interstrand crosslink repair, and meiotic recombination. To better understand the role of MEI-9 in these processes, we characterized 10 unique mutant alleles of mei-9. These include a P-element insertion that disrupts repair functions but not the meiotic function; three nonsense mutations,...
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