Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences

30 Sept 2016

Abstract excerpt

Genome stability is essential for all organisms. Translationally controlled tumour protein (TCTP) is a conserved protein associated with cancers. TCTP is involved in multiple intracellular functions, but its role in transcription and genome stability is poorly understood. Here, we demonstrate new functions of Drosophila TCTP (Tctp) in transcription and the stability of repeated sequences (rDNA and pericentromeric...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27687497
DOI: 10.1038/ncomms12988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequencesPMID 27687497Read ↗

The Drosophila trithorax group gene tonalli (tna) interacts genetically with the Brahma remodeling complex and encodes an SP-RING finger protein.Semantic proximity Read ↗

The RNA-binding activity of the Drosophila Brat protein is necessary for viability and mRNA regulation.Semantic proximity Read ↗

Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control.Semantic proximity Read ↗

Involvement of Telomerase Reverse Transcriptase in Heterochromatin MaintenanceSemantic proximity Read ↗

ZmSSRP1-mediated chromatin accessibility modulates maize development via regulation of ZmBRD1 transcription.Semantic proximity Read ↗

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.Semantic proximity Read ↗

Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition.Semantic proximity Read ↗

The Drosophila trithorax proteins contain a novel variant of the nuclear receptor type DNA binding domain and an ancient conserved motif found in other chromosomal proteins.Semantic proximity Read ↗

The chromosomal proteins JIL-1 and Z4/Putzig regulate the telomeric chromatin in Drosophila melanogaster.Semantic proximity Read ↗

The RNA binding activity of the first identified trypanosome protein with Z-DNA-binding domainsSemantic proximity Read ↗

TCTP directly regulates ATM activity to control genome stability and organ development in Drosophila melanogaster.Semantic proximity Read ↗

The human TPR protein TTC4 is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.