Article
Molecular characterization of mutant alleles of the DNA repair/basal transcription factor haywire/ERCC3 in Drosophila.
Genetics - 1 May 1999
Mounkes L C, Fuller M T
Abstract excerpt
The haywire gene of Drosophila encodes a putative helicase essential for transcription and nucleotide excision repair. A haywire allele encoding a dominant acting poison product, lethal alleles, and viable but UV-sensitive alleles isolated as revertants of the dominant acting poison allele were molecularly characterized. Sequence analysis of lethal haywire alleles revealed the importance of the nucleotide-binding...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
