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Article

Isolation of conditional mutations in genes essential for viability of Cryptococcus neoformans.

Current genetics - 1 Jun 2017

Ianiri Giuseppe, Boyce Kylie J, Idnurm Alexander

Abstract excerpt

Discovering the genes underlying fundamental processes that enable cells to live and reproduce is a technical challenge, because loss of gene function in mutants results in organisms that cannot survive. This study describes a forward genetics method to identify essential genes in fungi, based on the propensity for Agrobacterium tumefaciens to insert T-DNA molecules into the promoters or 5' untranslated regions...

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Topics

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Genes, Essential

Share to Mutagenesis, Insertional

Share to Proteasome Endopeptidase Complex

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Source

Open in PubMed Open full text

Identifiers

PMID: 27783209
DOI: 10.1007/s00294-016-0659-2
PMCID: PMC5405016

Genes

IDI1
MRPL37
NOP56
RPL17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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