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Genetic Manipulation of Cryptococcus neoformans

17 Jul 2018

Abstract excerpt

Cryptococcus neoformans is an opportunistic fungal pathogen, which causes life-threatening meningoencephalitis in immunocompromised individuals and is responsible for more than 1,000,000 infections and 600,000 deaths annually worldwide. Nevertheless, anti-cryptococcal therapeutic options are limited, mainly because of the similarity between fungal and human cellular structures. Owing to advances in genetic and...

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PMID: 30016567
DOI: 10.1002/cpmc.59

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