A Wor1-Like Transcription Factor Is Essential for Virulence of Cryptococcus neoformans

Abstract excerpt

Gti1/Pac2 transcription factors occur exclusively in fungi and their roles vary accord-ing to species, including regulating morphological transition and virulence, mating and secondary metabolism. Many of these functions are important for fungal pathogenesis. We therefore hypothesized that one of the two proteins of this family in Cryptococcus neoformans, a major pathogen of humans, would also control...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antifungal resistance and susceptibility
• Share to Fungal Infections and Studies
• Share to Plant Disease Resistance and Genetics