Article

Simple Growth Conditions Improve Targeted Gene Deletion in <i>Cryptococcus neoformans</i>

2025-01-04

Abstract excerpt

Cryptococcus neoformans infections are a significant cause of morbidity and mortality among AIDS patients and the third most common invasive fungal infection in organ transplant recipients. The cryptococcal cell wall is very dynamic and can be modulated depending on growth conditions. It was reported that when C. neoformans is grown in unbuffered yeast nitrogen base (YNB) for 48 hours, the pH of the media drastic...

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Identifiers and source

Literature Corpus work: 86693924-3936-5abc-8612-6de85733bb90
DOI: 10.1101/2024.12.18.629221

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