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Article

Association of cigarette smoking and microRNA expression in rectal cancer: Insight into tumor phenotype.

Cancer epidemiology - 1 Dec 2016

Mullany Lila E, Herrick Jennifer S, Wolff Roger K, Stevens John R, Slattery Martha L

Abstract excerpt

Smoking is known to influence messenger RNA (mRNA) expression in colorectal cancer (CRC) cases. As microRNAs (miRNAs) are known repressors of mRNAs, we hypothesize that smoking may influence miRNA expression, thus altering mRNA expression. Our sample consisted of 1447 CRC cases that had normal colorectal mucosa and carcinoma miRNA data and lifestyle data. We examined current smoking, current versus never and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27780077
DOI: 10.1016/j.canep.2016.10.011
PMCID: PMC5131860

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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