Association Between Smoking and Molecular Subtypes of Colorectal Cancer.

doi:10.1093/jncics/pkab056

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association Between Smoking and Molecular Subtypes of Colorectal Cancer.

JNCI cancer spectrum - 1 Aug 2021

Wang Xiaoliang, Amitay Efrat, Harrison Tabitha A, Banbury Barbara L, Berndt Sonja I, Brenner Hermann, Buchanan Daniel D, Campbell Peter T, Cao Yin, Chan Andrew T, Chang-Claude Jenny, Gallinger Steven J, Giannakis Marios, Giles Graham G, Gunter Marc J, Hopper John L, Jenkins Mark A, Lin Yi, Moreno Victor, Nishihara Reiko, Newcomb Polly A, Ogino Shuji, Phipps Amanda I, Sakoda Lori C, Schoen Robert E, Slattery Martha L, Song Mingyang, Sun Wei, Thibodeau Steven N, Toland Amanda E, Van Guelpen Bethany, Woods Michael O, Hsu Li, Hoffmeister Michael, Peters Ulrike

Abstract excerpt

Background: Smoking is associated with colorectal cancer (CRC) risk. Previous studies suggested this association may be restricted to certain molecular subtypes of CRC, but large-scale comprehensive analysis is lacking. Methods: A total of 9789 CRC cases and 11 231 controls of European ancestry from 11 observational studies were included. We harmonized smoking variables across studies and derived sex...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CpG Islands

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, ras

Share to Logistic Models

Share to Methylation

Share to Microsatellite Instability

Share to Observational Studies as Topic

Share to Proto-Oncogene Proteins B-raf

Share to Smokers

Source

Open in PubMed Open full text

Identifiers

PMID: 34377935
DOI: 10.1093/jncics/pkab056
PMCID: PMC8346704

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association Between Smoking and Molecular Subtypes of Colorectal Cancer.PMID 34377935Read ↗

Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathwaysSemantic proximity Read ↗

Risk Factors and Incidence of Colorectal Cancer According to Major Molecular Subtypes.Semantic proximity Read ↗

Cigarette smoking and colorectal cancer risk by molecularly defined subtypes.Semantic proximity Read ↗

Smoking and risk of colorectal cancer according to KRAS and BRAF mutation status in a Japanese prospective Study.Semantic proximity Read ↗

Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history.Semantic proximity Read ↗

Association between molecular subtypes of colorectal cancer and patient survival.Semantic proximity Read ↗

Colonoscopy and Reduction of Colorectal Cancer Risk by Molecular Tumor Subtypes: A Population-Based Case-Control Study.Semantic proximity Read ↗

Body mass index and molecular subtypes of colorectal cancer.Semantic proximity Read ↗

Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype.Semantic proximity Read ↗

Colonoscopy and reduction of colorectal cancer risk by molecular tumor subtypes: a population-based case-control studySemantic proximity Read ↗

Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype.Semantic proximity Read ↗

A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.