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Article

Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex.

Developmental cell - 24 Oct 2016

Oliva Carlos, Soldano Alessia, Mora Natalia, De Geest Natalie, Claeys Annelies, Erfurth Maria-Luise, Sierralta Jimena, Ramaekers Ariane, Dascenco Dan, Ejsmont Radoslaw K, Schmucker Dietmar, Sanchez-Soriano Natalia, Hassan Bassem A

Abstract excerpt

The axonal wiring molecule Slit and its Round-About (Robo) receptors are conserved regulators of nerve cord patterning. Robo receptors also contribute to wiring brain circuits. Whether molecular mechanisms regulating these signals are modified to fit more complex brain wiring processes is unclear. We investigated the role of Slit and Robo receptors in wiring Drosophila higher-order brain circuits and identified...

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Identifiers

PMID: 27780041
DOI: 10.1016/j.devcel.2016.09.028
PMCID: PMC5084709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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