Article
Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo.
Development (Cambridge, England) - 1 Feb 2000
Sun Q, Bahri S, Schmid A, Chia W, Zinn K
Abstract excerpt
Neural receptor-linked protein tyrosine phosphatases (RPTPs) are required for guidance of motoneuron and photoreceptor growth cones in Drosophila. These phosphatases have not been implicated in growth cone responses to specific guidance cues, however, so it is unknown which aspects of axonal pathfinding are controlled by their activities. Three RPTPs, known as DLAR, DPTP69D, and DPTP99A, have been genetically...
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