Article
Drosophila central brain formation requires Robo proteins.
Development genes and evolution - 1 Oct 2005
Nicolas Emmanuelle, Preat Thomas
Abstract excerpt
The Robo proteins have been extensively studied in the Drosophila embryonic ventral nerve cord, in which their expression level controls the midline crossing and optic lobe formation, but nothing is known about their activities during adult central brain formation. We have analyzed how Robo guidance cues influence central complex (CX) and mushroom body (MB) formation. Mutations of robo2 and robo3 confer a series...
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