Article
Association of genetic polymorphisms in the type II deiodinase gene with bipolar disorder in a subset of Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 31 Aug 2009
He Bing, Li Junyan, Wang Gang, Ju Weina, Lu Yadong, Shi Yongyong, He Lin, Zhong Nanbert
Abstract excerpt
OBJECTIVE: Genetic factors play a critical role in the etiology of bipolar disorder (BPAD). Previous studies suggested an association between thyroid dysfunction and BPAD. We hypothesize that genetic variations in the type II deiodinase (DIO2) gene that possibly alter the bioactivity of thyroid hormones are associated with BPAD. METHOD: A case-control association study was conducted in a subset of Chinese Han...
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