Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.

doi:10.1016/j.jalz.2016.09.002

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Article

Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Feb 2017

Mez Jesse, Chung Jaeyoon, Jun Gyungah, Kriegel Joshua, Bourlas Alexandra P, Sherva Richard, Logue Mark W, Barnes Lisa L, Bennett David A, Buxbaum Joseph D, Byrd Goldie S, Crane Paul K, Ertekin-Taner Nilüfer, Evans Denis, Fallin M Daniele, Foroud Tatiana, Goate Alison, Graff-Radford Neill R, Hall Kathleen S, Kamboh M Ilyas, Kukull Walter A, Larson Eric B, Manly Jennifer J, Haines Jonathan L, Mayeux Richard, Pericak-Vance Margaret A, Schellenberg Gerard D, Lunetta Kathryn L, Farrer Lindsay A

Abstract excerpt

INTRODUCTION: African Americans' (AAs) late-onset Alzheimer's disease (LOAD) genetic risk profile is incompletely understood. Including clinical covariates in genetic analyses using informed conditioning might improve study power. METHODS: We conducted a genome-wide association study (GWAS) in AAs employing informed conditioning in 1825 LOAD cases and 3784 cognitively normal controls. We derived a posterior...

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PMID: 27770636
DOI: 10.1016/j.jalz.2016.09.002
PMCID: PMC5318231

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ABCA7
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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