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Article

The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia.

Journal of hypertension - 1 Jan 2017

Thomsen Liv Cecilie V, McCarthy Nina S, Melton Phillip E, Cadby Gemma, Austgulen Rigmor, Nygård Ottar K, Johnson Matthew P, Brennecke Shaun, Moses Eric K, Bjørge Line, Iversen Ann-Charlotte

Abstract excerpt

OBJECTIVE: Preeclampsia is a complex heterogeneous disease commonly defined by new-onset hypertension and proteinuria in pregnancy. Women experiencing preeclampsia have increased risk for cardiovascular diseases (CVD) later in life. Preeclampsia and CVD share risk factors and pathophysiologic mechanisms, including dysregulated inflammation and raised blood pressure. Despite commonalities, little is known about...

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Identifiers

PMID: 27755385
DOI: 10.1097/HJH.0000000000001131
PMCID: PMC5131692

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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