Article
Genetic variants in 3'-UTRs of MTHFR in the pregnancies complicated with preeclampsia and bioinformatics analysis.
Journal of cellular biochemistry - 1 Jan 2018
Mohammadpour-Gharehbagh Abbas, Salimi Saeedeh, Keshavarzi Farshid, Saeidian Foozieh, Mousavi Mahdieh, Teimoori Batool, Esmaeilipour Maryam, Mokhtari Mojgan
Abstract excerpt
Preeclampsia (PE) as a pregnancy-specific disorder is the major cause of mortality and morbidity of mothers and fetuses. This study attempts to investigate the possible association between the 2572C>A (rs4846049) and 4869C>G (rs1537514) polymorphisms in the 3'- untranslated region of MTHFR gene and the risk of PE. A total of 198 patients diagnosed with PE and 171 unrelated, age matched healthy pregnant women,...
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