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Methylenetetrahydrofolate reductase gene (C677T) mutation as a genetic risk factor for preeclampsia in Ethiopian pregnant women.

Pregnancy hypertension - 1 Jun 2026

Yesuf Hassen Ahmed, Molla Meseret Derbew, Bekele Tesfahun, Melesse Mequanint, Hunie Kibur, Nigatu Amare, Yimer Yadelew

Abstract excerpt

INTRODUCTION: Preeclampsia (PE) is a significant contributor to maternal mortality. The methylenetetrahydrofolate reductase (MTHFR C677T) mutation has been linked to cardiovascular complications. However, data on MTHFR mutation status among Ethiopians remain limited. This study aimed to assess the association between MTHFR polymorphisms and the risk of preeclampsia among women receiving maternity care among...

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Identifiers

PMID: 41880730
DOI: 10.1016/j.preghy.2026.101459

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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