Preeclampsia, gestational hypertension, and cardiovascular disease risk: a genetic epidemiological study

Abstract excerpt

BACKGROUND AND AIMS: Observational studies show that women with hypertensive disorders of pregnancy have greater risk of cardiovascular disease later in life. Whether these associations reflect causal pathways is uncertain. This study used genetic epidemiology to explore the causal relevance of preeclampsia and gestational hypertension on cardiovascular disease. METHODS: Two-sample Mendelian randomization (MR)...