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Article

Folate metabolism gene polymorphisms MTHFR C677T and A1298C and risk for preeclampsia: a meta-analysis.

Journal of assisted reproduction and genetics - 1 May 2015

Wu Xiaoming, Yang Kunxian, Tang Xiaodan, Sa Yalian, Zhou Ruoyu, Liu Jing, Luo Ying, Tang Wenru

Abstract excerpt

OBJECTIVES: MTHFR C677T and A1298C have been associated with the risk of preeclampsia (PE), but with conflicting results. We performed this meta-analysis to derive a more precise estimation of the association between MTHFR polymorphisms and PE. STUDY DESIGN: An electronic search of PubMed and Chinese Biomedicine database was conducted to select studies for meta-analysis. 54 case controlled studies containing...

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Identifiers

PMID: 25758986
DOI: 10.1007/s10815-014-0408-8
PMCID: PMC4429450

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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