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GWAS of preeclampsia and hypertensive disorders of pregnancy uncovers genes related to cardiometabolic, endothelial and placental function

2022-05-21

Abstract excerpt

Preeclampsia is a vascular pregnancy disorder that affects 3-5% of all pregnancies. Genetic contribution to preeclampsia susceptibility is well established, but the actual risk loci have remained largely unknown. To make further discoveries of the underlying genetic architecture, we performed a new genome-wide association study (GWAS) for maternal preeclampsia and for two other combination phenotypes encompassing...

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Literature Corpus work
34d2cb90-f665-54b8-9ed0-a4f78703436e
DOI
10.1101/2022.05.19.22275002
Open publication

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GWAS of preeclampsia and hypertensive disorders of pregnancy uncovers genes related to cardiometabolic, endothelial and placental functionDOI 10.1101/2022.05.19.22275002
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