Article
Polymorphisms in the inflammatory pathway genes and the risk of preeclampsia in Sinhalese women.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Jan 2016
Andraweera Prabha H, Dekker Gustaaf A, Jayasekara Rohan W, Dissanayake Vajira H W, Roberts Claire T
Abstract excerpt
OBJECTIVE: Elevated pro-inflammatory cytokines play an important role in the pathogenesis of preeclampsia. We investigated the prevalence of functional polymorphisms in genes regulating inflammation in preeclamptic women. METHODS: One hundred seventy-five nulliparous Sinhalese women with preeclampsia (cases) and 171 normotensive women matched for age, ethnicity, parity and body mass index (BMI) (controls) were...
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